The Jews that flee the abomination of desolation will be the saints,not the people that do not believe in Jesus,for they will not flee,but the 2 witnesses will be there during the last three and one half years to witness to them,and at the end of that time they will be resurrected up.
The majority of Jews will not flee,but the 2 witnesses will turn them to the truth.
Israel is blinded in part,until the fulness of the Gentiles be come in,and so all Israel shall be saved.
The world has salvation for the first three and one half years,and after the 6th trumpet and they do not turn to God,He gives them the man of sin to rule over them.
When the world follows the beast,and takes the mark,then salvation is no longer available to them,and the fulness of the Gentiles will be come in,and then God will send Israel 2 witnesses to turn them to the truth,for Israel is blinded in part,until the fulness of the Gentiles be come in,so Israel is still blinded in part during the first three and one half years,so the witnesses do not witness during that time.
If the witnesses are sent to Israel during the first three and one half years,and they turn to the truth,then the beast will physically attack Israel in the middle of the 7 years period,for he persecutes all who hold the testimony of Jesus,but Israel is protected for the whole 7 years period from physical attack,so at the end of the last three and one half years Israel turned to the truth,and then the beast attacks them for their testimony of Jesus.
The majority of Jews will not run because they do not believe in Jesus,but only those that believe in Jesus will run for they know he is not God,and their Messiah.
The 2 witnesses are sent to Israel during the last three and one half years of the tribulation,for Israel is blinded in part,until the Gentiles that do not love God take the mark of the beast,and then salvation is no longer available to them,which is the fulness of the Gentiles be come in.
Rev 11:15 And the seventh angel sounded; and there were great voices in heaven, saying, The kingdoms of this world are become the kingdoms of our Lord, and of his Christ; and he shall reign for ever and ever.
Rev 11:16 And the four and twenty elders, which sat before God on their seats, fell upon their faces, and worshipped God,
Rev 11:17 Saying, We give thee thanks, O Lord God Almighty, which art, and wast, and art to come; because thou hast taken to thee thy great power, and hast reigned.
Rev 11:18 And the nations were angry, and thy wrath is come, and the time of the dead, that they should be judged, and that thou shouldest give reward unto thy servants the prophets, and to the saints, and them that fear thy name, small and great; and shouldest destroy them which destroy the earth.
Rev 11:19 And the temple of God was opened in heaven, and there was seen in his temple the ark of his testament: and there were lightnings, and voices, and thunderings, and an earthquake, and great hail.
When the 2 witnesses are resurrected up,and Israel is in the truth,then the 7th angel sounds,the 7th trumpet,and the wrath of God is poured upon the world,and the kingdoms of the world become the kingdoms of the Lord,and His Christ,which would not happen at the middle of the 7 years period.