Not directly to chaps 2&3 - but it does relate to Revelation in that the whore/harlot aka apostate Israel was judged in the war of 66-70 AD
Isaiah 4:4 is specifically speaking of the blood guilt of apostate Israel being purged:
Isa 4:4 When the Lord shall have washed away the filth of the daughters of Zion, and shall have purged the blood of Jerusalem from the midst thereof by the spirit of judgment, and by the spirit of burning.
Rev 17:16 “And the ten horns which you saw, and the beast, these will hate the harlot and will make her desolate and naked, and will eat her flesh and will burn her up with fire.
Rev 19:2 BECAUSE HIS JUDGMENTS ARE TRUE AND RIGHTEOUS; for He has judged the great harlot who was corrupting the earth with her immorality, and HE HAS AVENGED THE BLOOD OF HIS BOND-SERVANTS ON HER.”
Mat 23:35 so that upon you may fall the guilt of all the righteous blood shed on earth, from the blood of righteous Abel to the blood of Zechariah, the son of Berechiah, whom you murdered between the temple and the altar.
Matt 23:36 “Truly I say to you, all these things will come upon this generation."