KJV1611, there are extant manuscripts that date back to the 2nd century. I am not sure which family it belongs to, if any, since it is probable it was written between 100-175 AD at the absolute latest. The Rylands papyrus is a very important piece of parchment, seeing it is thought to be one of the earliest manuscripts that are currently known. Of course, it is extremely small, but it does show how early the NT has been around, so no one can say that the NT was written centuries after Jesus died. It was very interesting reading about how much studying has been done of this small piece of codex, because it does represent the earliest piece of Scripture yet discovered.
https://en.m.wikipedia.org/wiki/Rylands_Library_Papyrus_P52
The Vatican has a copy of a very early Codex Vaticanus thought to be from 300-350 AD. It was kept in the Vatican since it was discovered in 1475 AD century, which might be where you got that date. I believe it said in one article that it differs in numerous places from the TR.
https://en.m.wikipedia.org/wiki/Codex_Vaticanus
Of course, Codex Sinaiticus is the other highly significant text discovered by Count Tischendorf in 1859, the man who sheltered the Moravians while they had their 100 year prayer meeting, and started sending out the first missionaries in modern times. It was partly found in a monastery, and partly in their dump.
https://www.gotquestions.org/Codex-Sinaiticus-Vaticanus.html
For me, knowing that Daniel Wallace is right now in the libraries of Greece and Byzantine monasteries looking for copies of very early manuscripts is very important. This work continues, and who knows what remains to be found, when God's timing is right?
PS. As much as some people don't like to admit it, Wikipedia is usually quite reliable. Because the articles can and have been considerably edited, most of the material is accurate. Of course, we do need to check out other sources. I have read there are several studies of randomly looking for truth in Wikipedia articles, and they have been held up as being accurate to a high degree. (Not directed to you KJV1611, but other people who call me on using Wikipedia!)