If its not talking about the physical location, how can we ever know if this has been fulfilled or not? Your opinions, what does this verse and the verses surrounding it mean?
Hakawaka, the first rule of solid Bible interpretation is to take what is written in its PLAIN, LITERAL SENSE, unless there is a reason to see a metaphor or symbol. So let's look at the 6th vial judgment:
THE SIXTH VIAL JUDGEMENT AND THE BATTLE OF ARMAGEDDON
12 And the sixth angel poured out his vial upon the great river Euphrates; and the water thereof was dried up, that the way of the kings of the east might be prepared.
13 And I saw three unclean spirits like frogs come out of the mouth of the dragon, and out of the mouth of the beast, and out of the mouth of the false prophet.
14 For they are the spirits of devils [daimonion =demons], working miracles, which go forth unto the kings of the earth and of the whole world, to gather them to the battle of that great day of God Almighty.
15 Behold, I come as a thief. Blessed is he that watcheth, and keepeth his garments, lest he walk naked, and they see his shame.
16 And he gathered them together into a place called in the Hebrew tongue Armageddon.
A. Firstly let's see what is literal and what is symbolic or metaphorical. (1) The river Euphrates is literal. (2) the false prophet is literal, (3) devils or demons are literal, (4) battle is literal, (5) the great day of God Almighty is literal, (6) the kings of the earth and the whole world is literal and (7) Armageddon in literal. At the same time, (1) the dragon, (2) the beast, and (3) frogs are metaphorical for Satan, the Antichrist, and unclean spirits.
B.
The focus is on the Battle of Armageddon. Armageddon is from the Hebrew
har Megiddo, which is a plain not too far from the city of Jerusalem. In verse 16, "he". refers to Satan. So the devil along with these evil spirits causes the rulers of the nations in the whole world to gather together against Jerusalem, the Jews, and Christ Himself. They falsely believe they can actually defeat the Lord Jesus Christ.
C.
Revelation 19: 17-21 completes the picture. All the carrion birds are invited to feast on these enemies of Christ, and the Antichrist and the False Prophet are killed, and cast into the Lake of Fire. Satan's turn will be after the battle of Gog and Magog (Rev 20).
17 And I saw an angel standing in the sun; and he cried with a loud voice, saying to all the fowls that fly in the midst of heaven, Come and gather yourselves together unto the supper of the great God; 18 That ye may eat the flesh of kings, and the flesh of captains, and the flesh of mighty men, and the flesh of horses, and of them that sit on them, and the flesh of all men, both free and bond, both small and great. 19 And I saw the beast, and the kings of the earth, and their armies, gathered together to make war against him that sat on the horse, and against his army. 20 And the beast was taken, and with him the false prophet that wrought miracles before him, with which he deceived them that had received the mark of the beast, and them that worshipped his image. These both were cast alive into a lake of fire burning with brimstone. 21 And the remnant were slain with the sword of him that sat upon the horse, which sword proceeded out of his mouth: and all the fowls were filled with their flesh.
The "sword" proceeding out of the mouth of Christ is nothing other than the Sword of the Spirit, which is the Word of God. Christ may speak only one word, and this evil multitude will be killed supernaturally. This happens at the Second Coming of Christ.