Thank you. I am all for good clean humor, truly. I just don't think joking about someone taking drugs should be here. My opinion, thank you again.
"The geek in me did it on a whim..."
LSD is the most commonly known substance that might produce such an effect as was described in the image.
And, of course, caffeine alone should never produce such an effect.
I did not mean to "personalize" it; rather, it was merely a "scientific extension" of the joke suggested in the image - a "slightly heightened" level of joke for those who would understand the significance.