I don't waste my money on them. I invest in stocks, mutual funds, and may start looking into precious metals. Despite the economic lunacy out there, I stand a much better chance of winning in the end.
Also... I once promised God that I would never gamble, and it is a promise I've kept.
Would I judge another Christian for buying a ticket? I don't know... I might look at them quizzically, but I don't know if it is necessarily sinful, either.