The Hebrew literally says
... and YHWH intercedes in him all of our depravity. Isaiah 53:6
Yes, The Hebrew can be used to make intercession for us.
7003 פָּגַע (
pā·ḡǎʿ): v.; ≡ Str 6293; TWOT 1731—
1. LN 19.1–19.13 (qal)
strike, i.e., make physical impact on an object which will result in harm or death (1Sa 22:17, 18; Jdg 15:12; 18:25); (hif)
strike, impact upon (Job 36:32+);
2. LN 15.75–15.80 (qal)
meet, come to, i.e., come to an area by linear movement and come near another object in an encounter (Ge 28:11; 32:2[EB 1]; Ex 5:20);
3. LN 33.347–33.348 (qal)
intercede for, spare, help, i.e., to speak on behalf of someone else, with a focus that the encounter is effective (Ge 23:8; Isa 47:3); (hif)
make intercession, intervene (Isa 53:12; 59:16+);
4. LN 84.1–84.15 (qal)
touch, extend, border, i.e., reach out from a source to an extremity (Jos 19:11);
5. LN 33.299–33.306 (qal)
plead with, i.e., speak in a way to encourage a particular behavior (Ru 1:16; Job 21:15; Jer 7:16; 27:18), note: this can be to either God or mankind; (hif)
plead, urge (Jer 15:11; 36:25+);
6. LN 13.1–13.47 (qal)
cause, strike, i.e., cause a state to exist (Ex 5:3); (hif)
cause, make encounter (Isa 53:6+)
Again, redemption He took the penalty of my sin.
Think also of the scapegoat.