You just don't know, Nuke. I haven't answered this thread before because on a typical day I carry:
* lip balm
* dental floss, paste, brush (You just never know!)
* emery board and clippers
* comb & extra hair bands (Sometimes even a male co-worker needs one.)
* magazine, book, letter-writing materials, pens in at least 4 colors (People always ask for extra pens, too, so I carry about 6 at at time.)
* hand sanitizer/lotion
* Band-aids.
* box cutter and holder
* eye drops
* 2 water bottles
Need I go on?
Zippers. I demand zippers.
I learned years ago from trying to buy bags with everything from toggles to drawstrings to magnetic clips and lost tons of stuff along the way.