Folks, this is how big these nebulae are... consider this.
The Orion Nebula, e.g., is about 10 to 25 light-years across. This is about 60 to 150 trillion miles. That nebula would encompass our sun, Sirius (8.7 LY away), Procyon (11.45 LY away), Altair (16.7 LY), almost all the way to Vega (~27 LY away).
To give you an idea of how far away this thing is, this ~25 trillion LY-wide cloud is a small blueish smudge in the winter sky. 25 trillion LY wide, at ~1,500 LY away, looks like a smudge slightly larger than the stars comprising the constellation. (The above-mentioned stars would fit into that smudge.)
And, you must bear in mind that this thing's a stellar "neighbor". Its distance from us is only about 1.5% the width of our galaxy.
The Andromeda galaxy's about 2 million LY away. That's about 20 Milky Way galaxy diameters. And, that's just a galactic neighbor.
There is no Other.