Yes please be careful with the man made stuff it kills even the beneficial's (bee's) ,,,,,,,,,,,
ps if you take the weed killer your trying and put it in a sandwich bag then stick the end of the vine in the sandwich bag and use a bread tie to hang it from something the vine will take up the liquid into the vine and eventual kill the root. Think PH, if the vine likes a PH of 6.5 change it to something it don't like with either vinegar or baking soda(natural stuff).