Paul to the Corinthians: "14 I do not write these things to shame you, but as my beloved children I warn you. 15 For though you might have ten thousand instructors in Christ, yet you do not have many fathers; for in Christ Jesus I have begotten you through the gospel. 16 Therefore I urge you, imitate me. 17 For this reason I have sent Timothy to you, who is my beloved and faithful son in the Lord, who will remind you of my ways in Christ, as I teach everywhere in every church."
Each church in Revelation had a singular angel: a set man, a leader charged with the care of the saints.
If we use the house model of gathering, where "house" is the word for a multi-generational family, we can find it in scripture, first with the Jews, in Joshua:
14 In the morning therefore you shall be brought according to your tribes. And it shall be that the tribe which the Lord takes shall come according to families; and the family which the Lord takes shall come by households; and the household which the Lord takes shall come man by man.
So, the Lord's house is arranged by tribes, families, households, and lastly by the individuals, but the husband is head of the wife. The husband, therefore, may properly represent his wife in all matters.
If we start with one man, he represents all within his natural sphere: wife and children (Eve was the first "son of God, son of man since she came from Adam and was fashioned after his being). Since we are dealing with spiritual families, these would be his wife and his spiritual sons (male and female) over whom he watches for their souls.
If his spiritual sons have spiritual sons, they become a household because the first man represents sons over whom he has no direct oversight.
As the fathers mature, and more sons come in, they represent a family or a "house": a multi-generational family of fathers and sons. They are to see themselves as one "house" or "family" to avoid sectarianism ("I am of Apollos, I am of Cephas, I am of Christ", etc.). A father in Christ will not tolerate such divisions among the sons. When the fathers of the family assemble to one man from whom their faith was imparted, they assemble as a tribe. Together, all the tribes of God make up the nation of God.
It was always God's intent that the natural family represent the spiritual family (1 to1) but, because of sin, spiritual fathers who are not natural fathers became necessary. For example, my spiritual father is a black man. He clearly is not my natural father. He is the man from whom my faith was born and he watches over my soul. This is how God is building his house.