Ah yes. Man can thwart God.
Happens all the time.
Luke 7:30
(KJV) But the Pharisees and lawyers rejected the counsel of God against themselves, being not baptized of him.
(NIV) But the Pharisees and experts in the law rejected God's purpose for themselves, because they had not been baptized by John.)
(ESV) but the Pharisees and the lawyers rejected the purpose of God for themselves, not having been baptized by him.)
(NKJV) But the Pharisees and lawyers rejected the will of God for themselves, not having been baptized by him.
(NRSV) But by refusing to be baptized by him, the Pharisees and the lawyers rejected God's purpose for themselves.)
No, but man does have free will, and can choose to either accept or reject God.